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Acute vs Delayed Iron: Effect On Red Cell Iron Incorporation In Severe Malaria

Key Contact: Sarah Cusick

Approximately 1 million children < age 5 living in sub-Saharan Africa die from severe anemia annually. This severe anemia frequently results from coexisting iron deficiency and malaria infection, but the standard of care, concurrent iron therapy, and antimalarial treatment has proven ineffective at... learn more.

Vitamin D Status: Association with iron therapy effectiveness and risk of malaria infection

Key Contact: Sarah Cusick

In many regions, iron deficiency and malaria co-occur and afflict young children disproportionately. However, treatment of iron deficiency in children with malaria has proven ineffective at improving iron status and in some studies has worsened malaria (4-6), leaving millions of children at risk fo... learn more.

Thailand Hub

Key Contact: Erin Mann

The University of Minnesota Academic Health Center (AHC) launched the Thailand Hub in April 2016, building on joint education initiatives and collaborative research studies over the last 25 years. The Hub is anchored by strong collaborations between the University of Minnesota and universities in... learn more.

Operational Research for Cryptococcal Antigen Screening (ORCAS) of HIV Patients

Key Contact: David Boulware

This randomized clinical trial tests improved therapy for asymptomatic cryptococcal antigenemia.... learn more.

Optimizing iron status while minimizing morbidity in HIV-infected Ugandan children

Key Contact: Sarah Cusick

Randomized, placebo-controlled trial of the effect of iron supplementation in moderately anemic HIV-infected children on iron status, gut microbiome and frequency of malaria and other episodes of infectious diseases.... learn more.

Uptake of and barriers to HPV vaccination among adolescent girls in rural Uganda

Key Contact: Nicole Basta

Pilot study collaboration between UMN School of Public Health and Makerere University's Child Health and Development to assess vaccine uptake.... learn more.

Reversing tissue fibrosis to improve immune reconstitution in HIV

Key Contact: Timothy Schacker

Clinical trial investigates antifibrotic therapy in relation to lymph node architecture and fibrosis in persons with and without HIV in Uganda, to assess their potential as HIV reservoirs.... learn more.

Phased implementation of cryptococcal screening in South Africa

Key Contact: David Boulware

This stepped-wedge randomized trial will roll out cryptococcal antigen screening nationwide in collaboration with the South African National Institute of Communicable Diseases and US CDC.... learn more.

HIV-associated mycardial fibrosis

Key Contact: Jason Baker

This pilot project investigates the interaction of HIV and cardiovascular disease in a cohort combining investigators in cardiac MRI with immunologic profiling. ... learn more.

Sensitivity of lung ultrasound in children with radiographic pneumonia

Key Contact: Stephen Dunlop

Quality improvement initiative aiming at improving care in a resource-limited setting.... learn more.

HIV NIH Clinical Trials Network in Nanning, China

Key Contact: Eric Chu

HIV clinical trials site in Nanning, China allows Chinese-speaking US medical opportunities for HIV research at center affiliated with NIH HIV clinical trials network for HIV prevention (HPTN), preventing mother-to-child transmission (IMPAACT).... learn more.

Fatty liver and fibrosis during immune reconstitution of HIV-infected patients in Argentina

Key Contact: Jose Debes

Translational hepatology research located at Hospital Rawson, Hospital Privado, and Instituto de Virologica in Cordoba, Argentina.... learn more.

Improving diagnosis with point of care ultrasound in the rural archipelago of Western Panama

Key Contact: Jonathan Kirsch

Project seeks to define etiologies of febrile illness and to implement a diagnostic testing algorithm using point of care testing strategies.... learn more.

Novel therapeutic treatment of hepatitis B virus infection

Key Contact: Louis Mansky

This project is part of an initiative to forge new collaborative research efforts between the University of Minnesota and Guangxi CDC.... learn more.

Factors associated with longevity in Guangxi, China

Key Contact: Fang Yu

This project is part of an initiative to forge new collaborative research efforts between the University of Minnesota and Guangxi CDC.... learn more.

Differential miRNA profiles HCC cases and controls with HBV with BCP double mutations

Key Contact: Guisheng Song

This project is part of an initiative to forge new collaborative research efforts between the University of Minnesota and Guangxi CDC.... learn more.

Secondhand smoke exposure and carcinogen uptake in elementary school children in Nanning, Guang

Key Contact: Irina Stepanov

This project is part of an initiative to forge new collaborative research efforts between the University of Minnesota and Guangxi CDC.... learn more.

Hepatitis E infection in immunosuppressed hosts

Key Contact: Jose Debes

This project addresses risk factors for Hepatitis E infection in individuals with HIV, transplant recipients, patients on dialysis, etc. It also studies the role of hepatitis E in progression to liver fibrosis and cirrhosis. It is performed in collaboration with Virology Institute of Cordoba, Hospit... learn more.

Hepatocellular carcinoma in South America

Key Contact: Jose Debes

This is a multinational project involving multiple countries in South America. The study aims to understand risk factors for liver cancer in the region. It also studies the effect of specific therapies for liver cancer and the role of region-specific infections and customary habits in the developmen... learn more.

Hepatitis B in Tanzania

Key Contact: Jose Debes

This project aims to understand the knowledge as well as social impact of hepatitis B infection in rural Africa. We run surveys to understand hepatitis B knowledge among health care providers as well as patients. We also evaluate the clinical progression of hepatitis B (to liver cancer and cirrhosis... learn more.

Doris Duke Fellowship Site in Family Medicine

Key Contact: Dr. Diego Garcia-Huidobro

Current research activities include "Development and evaluation of a parenting intervention to prevent illicit substances among Chilean youth" and "Needs assessment of family members receiving care in hospital units." Both of these projects aim to develop interventions that include the family as a u... learn more.

Dengue fever in Colombia: improving diagnosis

Key Contact: Dr. Jonathan Kirsch

This Doris Duke fellowship site will enable fellows to gain experience in the following clinical research activities: Chart review, clinical site visits, statistical analysis of data from charts and collaborative work to create new diagnostic criteria. Spanish language skills are a requirement for c... learn more.

Mfangano Community Health Field Station

Key Contact: Chas Salmen

The Mfangano Community Health Field Station is a community-rooted enterprise launched in collaboration between the University of Minnesota, Maseno University, and the Organic Health Response (OHR) of Mfangano Island in Kenya. We seek to advance community-based research, bilateral training opportu... learn more.

Improving primary care diagnosis and classification of dengue fever with bedside ultrasound

Key Contact: Jonathan Kirsch

The incidence of dengue virus (DENV) infection has increased dramatically throughout much of the world over the past few decades, and, among arboviral diseases, causes the highest burden of human morbidity and mortality. We hypothesize that portable ultrasound will help classify and risk-stratify DE... learn more.

Childhood Cancer Research

Key Contact: Logan Spector

Childhood cancer research.... learn more.

Clinical Research: Meningitis randomized clinical trials

Key Contact: David Boulware

Investigators from Minnesota and Uganda have a long-standing research collaboration to improve the outcomes of people living with HIV/AIDS afflicted with cryptococcal meningitis or TB meningitis. Since 2006, collaborative research has sought to innovate international treatment guidelines for care of... learn more.

Liver Cancer Predictors in South America - clinical and laboratory research site

Key Contact: Jose Debes

Hub for multinational study (6 countries in South America) addressing demographics and clinical variables for liver cancer as well as blood biomarkers for liver cancer and cholangiocarcinoma.... learn more.

Risk factors for Hepatitis E Infection in immune-compromised individuals

Key Contact: Jose Debes

Assessment of clinical and laboratory factors related to the prevalence of hepatitis E infection in Argentina. This site includes a laboratory component. ... learn more.

Evaluation of clinical variables related to liver cancer in hepatitis B-infected individuals

Key Contact: Jose Debes

This project has a cross-sectional portion and a prospective portion, both looking at variables related to early-onset liver cancer in individuals infected with hepatitis B. ... learn more.

Nonalcoholic Fatty Liver Disease (NAFDL) in South America

Key Contact: Jose Debes

Hub for a multinational study in South America addressing demographic, clinical and biopsy-related variables impacting non-alcoholic liver disease in the region. ... learn more.

Hepatitis B-related HCC: cross-sectional and prospective evaluation

Key Contact: Jose Debes

This project evaluates clinical and laboratory markers for liver cancer in individuals infected with HBV in Ethiopia. ... learn more.

Standardized Patients to Measure & Address Stigma: An HIV Prevention Engagement Strategy

Key Contact: Kumi Smith

The 2018 World AIDS Day theme, “Know your Status,” highlighted global concern over lack of progress in HIV testing uptake. Nearly a quarter of people living with HIV remain untested, depriving them of opportunities to enter into the HIV prevention continuum and access to proven prevention tools ... learn more.

Partnership in the Study of Aquatic Systems

Key Contact: Noelle Noyes

The Noyes Lab is teaming up with Henning Sørum at Norwegian University of Life Sciences and Katrine Lekang at University of Oslo in a project that aims to develop new metrics for quantifying selection pressures on the resistome while also understanding how aquatic systems behave in the presence of ... learn more.

Rwanda Human Resources for Health Program

Key Contact: Jennifer Rickard

The Ministry of Health in Rwanda has partnered with a consortium of top US institutions of medicine, nursing, health management, and dentistry who are committed to sending faculty to schools of medicine and nursing, and hospitals throughout Rwanda. The aim of this program is to improve the quantity ... learn more.

Uganda Surgery Research Collaboration

Key Contact: Jennifer Rickard

Research to develop and maintain an operative database in Mulago referral Hospital.... learn more.