Global Health Impact Map
Improving primary care diagnosis and classification of dengue fever with bedside ultrasound
Key Contact: Jonathan Kirsch
Activity Dates: 2018 to 2019
The incidence of dengue virus (DENV) infection has increased dramatically throughout much of the world over the past few decades, and, among arboviral diseases, causes the highest burden of human morbidity and mortality. We hypothesize that portable ultrasound will help classify and risk-stratify DENV-infected patients beyond the standard clinical evaluation by identifying early plasma leakage.
Specific Aim 1: To describe ultrasound findings in patients in Colombia with suspected dengue fever by clinical phase and fever day, including novel measurements like pulmonary B-lines.
Specific Aim 2: To establish the prevalence, clinical meaning, and factors associated with plasma leakage in suspected dengue fever patients attending ambulatory health care services in an endemic area in Colombia.
Specific Aim 3: To determine if trained researchers can reliably perform bedside ultrasound and thus aid in the correct classification of dengue severity.
This study is eligible for CGHSR Scholar applications. Students should inquire with Dr. Kirsch and submit applications through https://globalhealthcenter.umn.edu/CGHSRScholars
Academic Health Center Units
Department of Medicine
Other Academic Health Center Units
Center for Global Health and Social Responsibility (CGHSR)
Lyda Osorio, MD PhD, Associated Professor, Universidad del Valle (UniValle), Escuela de Salud Pública, Cali, Colombia
Katie B Anderson, MD PhD MSPH CTropMed, University of Minnesota Medical School
Stephen Dunlop MD, MPH, CTropMed, FACEP, Hennepin County Medical Center & University of Minnesota Medical School
Universidad del Valle (UniValle), Escuela de Salud Pública, Cali, Colombia
UMN CGHSR Global Health Seed Grant (2018)
Infectious Disease, Zoonotic Disease