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Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis (ASTRO-CM)

Key Contact: David R Boulware | Visit Activity Website

Activity Dates: Feb 2013 to present

Country(ies): Uganda

Contact Information

Activity Description

This project is a clinical trial testing whether sertraline has antifungal efficacy for treatment of cryptococcal meningitis. Cryptococcal meningitis is the most common cause of meningitis in sub-Saharan Africa and causes 20-25% of AIDS-related mortality.

Activity Types


Academic Health Center Units

Medical School
     Global Health Pathway

Other Collaborators

David Meya, Kirsten Nielsen, Paul Bohjanen, Kathy Huppler Hullseik, Joshua Rhein, Nate Bahr

Partner Organizations

Infectious Disease Institute, Makerere University


University of Minnesota - Clinical and Translational Science Institute

Special Tags

Doris Duke Clinical Research Fellowship Site, Fogarty Global Health Fellowship Site